Playing in the same division means both sides are deeply familiar with each other,Zaino Fjallraven Kanken Offerta; there won't be many secrets on display here.
That the Niners have struggled in the Pacific Northwest is, well, tangible: They were outscored 71-16 in their last two visits, Harbaugh's two worst losses. They're an experienced outfit in pressure situations, though, so the supersonic noise from the 12th Man in the stands shouldn't affect them.
