In 1981, Gamble joined the Eagles as a volunteer assistant coach under Dick Vermeil and became a full-time staffer a year later, coaching special teams and tight ends. He moved into the front office as director of football operations in 1984, and a year later he was named general manager by owner Leonard Tose.
In 1986, he became team president,Adam Duvall Jersey, a position he held until 1994.